Case 28

Patient #28 is a 58-year-old-man who has undergone two separate two-stage exchange arthroplasties for his right hip periprosthetic infection. He has undergone multiple rounds of intravenous antibiotics and oral suppressive antibiotics as well. He has developed another abscess and draining wound about his right hip. Prior to his hip surgery, he was a young, active male. Without control of this infection he would either need to undergo a resection arthroplasty which would leave him with considerable morbidity and decreased function or be at risk for developing sepsis secondary to his chronic right hip infection. APT identified a lytic S. aureus bacteriophage and provided therapy. The patient received an intraoperative phage dose followed by 7 weeks of IV bacteriophage therapy, with no reported adverse events.