Case 29

Patient #29 was a 61-year-old female with past medical history significant for hypertension, obesity who was admitted to the hospital from a nursing home with difficulty breathing for one day. Initial assessment in the emergency department found her to be in respiratory failure due to Covid19 pneumonia and in shock. She was intubated due to her respiratory issues. Phage was given in 3 IV doses administered over 2 days. Sputum culture was positive for CRAB (Carbapenem-resistant Acinetobacter baumannii) which was resistant to all antibiotics but demonstrated intermediate resistance to tigecycline and meropenem. No adverse events were reported as related to phage therapy. The patient expired prior to receiving a 4th dose on Day 3.