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Recent studies demonstrate that bacterial species are present within the tumor microenvironment. Fusobacterium nucleatum is significantly enriched in human colorectal carcinomas, and its presence correlates with advanced tumor stage and poor prognosis.
Title Broad Host Range Bacteriophage For Reduction Of Klebsiella Pneumoniae As Potential Therapy In Primary Sclerosing Cholangitis (Psc) Jorunal AASLD Conference 2020 DescriptionPrimary sclerosing cholangitis (PSC) is a rare immunerelated disease. Strains of Klebsiella pneumoniae (KP) have been suggested as a potential therapeutic target in PSC, as KP isolated from PSC patients’ stool were shown to cause Th17 immune stimulation and an increase in gut permeability in germ-free WT or DDC-treated mice
Title Activity of Bacteriophage Against Multidrug Resistant Klebsiella Pneumoniae Jorunal IDWeek Conference 2020 DescriptionThe prevalence of extended-spectrum beta-lactamase (ESBL) producing and carbapenem resistant (CR) Klebsiella pneumoniae (KP) has significantly risen worldwide. Infections due to these bacteria are of increasing clinical concern and associated with high mortality across different infection types
Title Development of natural bacteriophages for skin care Jorunal AAD Conference, March 2020 DescriptionThe extensive use of topical and oral antibiotics to address this condition has led to widespread antibiotic resistance in C. acnes. Furthermore, the common growth formation of these bacteria in polysaccharide-rich biofilm matrices also protects them from antibiotic activity
Title Novel phages targeting intratumor associated fusobacterium nucleatum Jorunal AACR Conference, Orlando FL, February 2020 DescriptionRecent studies demonstrate that bacterial species are present within the tumor microenvironment
Title Use of a bacteriophage cocktail for eradication of Klebsiella pneumoniae in Primary Sclerosing Cholangitis Jorunal AASLD Conference, Boston US, November 2019 DescriptionGrowing Evidence of Role of Harmful Bacteria in Chronic Diseases
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