Publications

Featured Publications

Novel Analysis of Fusobacterium Nucleatum Species in Human Colorectal Cancer and Engineering of Therapeutic Bacteriophage ESMO-IO

Recent studies demonstrate that bacterial species are present within the tumor microenvironment. Fusobacterium nucleatum is significantly enriched in human colorectal carcinomas, and its presence correlates with advanced tumor stage and poor prognosis.

Broad Host Range Bacteriophage For Reduction Of Klebsiella Pneumoniae As Potential Therapy In Primary Sclerosing Cholangitis (Psc) AASLD Conference 2020

Primary sclerosing cholangitis (PSC) is a rare immunerelated disease. Strains of Klebsiella pneumoniae (KP) have been suggested as a potential therapeutic target in PSC, as KP isolated from PSC patients’ stool were shown to cause Th17 immune stimulation and an increase in gut permeability in germ-free WT or DDC-treated mice

Bacteriophage delivery into tumor associated bacteria CRI-CIMT-EATI-AACR, International Cancer Immunotherapy Conference, Paris France, September 2019

Recent studies revealed that bacterial species present within the tumor microenvironment may promote tumor growth, enable tumor cells to evade the immune system and provide resistance to cancer therapeutics
Use of a targeted bacteriophage cocktail for the treatment of Inflammatory Bowel Disease UEG Conference, Barcelona Spain

Dysbiosis is associated with inflammatory bowel disease (IBD) and, together with genetic and environmental elements, is implicated in perpetuating chronic inflammation

All Publications

Title Journal Description
Title Novel Analysis of Fusobacterium Nucleatum Species in Human Colorectal Cancer and Engineering of Therapeutic Bacteriophage Jorunal ESMO-IO Description

Recent studies demonstrate that bacterial species are present within the tumor microenvironment. Fusobacterium nucleatum is significantly enriched in human colorectal carcinomas, and its presence correlates with advanced tumor stage and poor prognosis.

Title Broad Host Range Bacteriophage For Reduction Of Klebsiella Pneumoniae As Potential Therapy In Primary Sclerosing Cholangitis (Psc) Jorunal AASLD Conference 2020 Description

Primary sclerosing cholangitis (PSC) is a rare immunerelated disease. Strains of Klebsiella pneumoniae (KP) have been suggested as a potential therapeutic target in PSC, as KP isolated from PSC patients’ stool were shown to cause Th17 immune stimulation and an increase in gut permeability in germ-free WT or DDC-treated mice

Title Activity of Bacteriophage Against Multidrug Resistant Klebsiella Pneumoniae Jorunal IDWeek Conference 2020 Description

The prevalence of extended-spectrum beta-lactamase (ESBL) producing and carbapenem resistant (CR) Klebsiella pneumoniae (KP) has significantly risen worldwide. Infections due to these bacteria are of increasing clinical concern and associated with high mortality across different infection types

 Title Development of natural bacteriophages for skin care Jorunal AAD Conference, March 2020 Description

The extensive use of topical and oral antibiotics to address this condition has led to widespread antibiotic resistance in C. acnes. Furthermore, the common growth formation of these bacteria in polysaccharide-rich biofilm matrices also protects them from antibiotic activity

 Title Novel phages targeting intratumor associated fusobacterium nucleatum Jorunal AACR Conference, Orlando FL, February 2020 Description

Recent studies demonstrate that bacterial species are present within the tumor microenvironment

Title Use of a bacteriophage cocktail for eradication of Klebsiella pneumoniae in Primary Sclerosing Cholangitis Jorunal AASLD Conference, Boston US, November 2019 Description

Growing Evidence of Role of Harmful Bacteria in Chronic Diseases

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